Vydura 75mg is a medication specifically designed for the treatment and prevention of migraines in adults. It contains the active ingredient rimegepant, which belongs to a class of drugs known as CGRP (calcitonin gene-related peptide) receptor antagonists. This medication is notable for its dual action, providing both acute relief from migraine attacks and preventive treatment for individuals experiencing frequent migraines.
Rimegepant works by blocking the receptors that CGRP binds to during a migraine attack. CGRP is a neuropeptide that plays a significant role in the development of migraine symptoms, including headache and associated discomfort. By inhibiting this receptor, Vydura 75mg effectively reduces the pain and other symptoms associated with migraines.
Vydura 75mg comes in the form of freeze-dried wafers that dissolve under the tongue. The recommended usage is: For acute treatment: One wafer can be taken once daily as needed. For preventive treatment: One wafer should be taken every other day. This method of administration allows for rapid absorption into the bloodstream, leading to quicker onset of action compared to traditional oral tablets.
Clinical studies have demonstrated that Vydura is more effective than placebo in treating migraines. In trials involving approximately 3,500 adults:
- About 20% of patients taking Vydura reported being headache pain-free within two hours, compared to 12% on placebo.
- Additionally, around 36% experienced relief from one or more migraine-associated symptoms (such as photophobia or phonophobia) within two hours after taking Vydura, versus 27% on placebo.
In preventive studies, patients using Vydura experienced an average reduction of 4.3 days with migraines over four weeks compared to 3.5 days for those on placebo.
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